TY  - JOUR
A1  - Pliquett, Rainer U.
A1  - Asbe-Vollkopf, Aida
A1  - Scheuermann, Ernst-Heinrich
A1  - Gröne, Elisabeth
A1  - Probst, Michael
A1  - Geiger, Helmut
A1  - Hauser, Ingeborg A.
T1  - Cholesterol-crystal embolism presenting with delayed graft function and impaired long-term function in renal transplant recipients : two case reports
T2  - Journal of Medical Case Reports
N2  - Introduction Impaired renal function and/or pre-existing atherosclerosis in the deceased donor increase the risk of delayed graft function and impaired long-term renal function in kidney transplant recipients. Case presentation We report delayed graft function occurring simultaneously in two kidney transplant recipients, aged 57-years-old and 39-years-old, who received renal allografts from the same deceased donor. The 62-year-old donor died of cardiac arrest during an asthmatic state. Renal-allograft biopsies performed in both kidney recipients because of delayed graft function revealed cholesterol-crystal embolism. An empiric statin therapy in addition to low-dose acetylsalicylic acid was initiated. After 10 and 6 hemodialysis sessions every 48 hours, respectively, both renal allografts started to function. Glomerular filtration rates at discharge were 26 ml/min/1.73 m2 and 23.9 ml/min/1.73 m2, and remained stable in follow-up examinations. Possible donor and surgical procedure-dependent causes for cholesterol-crystal embolism are discussed. Conclusion Cholesterol-crystal embolism should be considered as a cause for delayed graft function and long-term impaired renal allograft function, especially in the older donor population.
Y1  - 2009
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/6501
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30-65987
N1  - © 2009 Pliquett et al; licensee Cases Network Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 3
IS  - 6839
ER  -