TY - JOUR A1 - Nollmann, Friederike I. A1 - Dowling, Andrea A1 - Kaiser, Marcel A1 - Deckmann, Klaus A1 - Grösch, Sabine A1 - French-Constant, Richard A1 - Bode, Helge Björn T1 - Synthesis of szentiamide : a depsipeptide from entomopathogenic Xenorhabdus szentirmaii with activity against Plasmodium falciparum T2 - Beilstein journal of organic chemistry N2 - The synthesis of the recently characterized depsipeptide szentiamide (1), which is produced by the entomopathogenic bacterium Xenorhabdus szentirmaii, is described. Whereas no biological activity was previously identified for 1, the material derived from the efficient synthesis enabled additional bioactivity tests leading to the identification of a notable activity against insect cells and Plasmodium falciparum, the causative agent of malaria. KW - cyclic depsipeptide KW - esterification KW - natural product KW - szentiamide KW - Xenorhabdus Y1 - 2012 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/25206 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-252060 SN - 1860-5397 VL - 8 SP - 528 EP - 533 PB - Hindawi CY - New York, NY ER -