TY  - JOUR
A1  - Ferstl, Philip
A1  - Reinheimer, Claudia
A1  - Jozsa, Katalin
A1  - Zeuzem, Stefan
A1  - Kempf, Volkhard A. J.
A1  - Waidmann, Oliver
A1  - Grammatikos, Georgios
T1  - Severe infection with multidrug-resistant Salmonella choleraesuis in a young patient with primary sclerosing cholangitis
T2  - World journal of gastroenterology
N2  - Massive global spread of multidrug-resistant (MDR) Salmonella spp. expressing extended-spectrum beta-lactamase (ESBL) and additional resistance to fluoroquinolones has often been attributed to high international mobility as well as excessive use of oral antibiotics in livestock farming. However, MDR Salmonella spp. have not been mentioned as a widespread pathogen in clinical settings so far. We demonstrate the case of a 25-year-old male with primary sclerosing cholangitis who tested positive for MDR Salmonella enterica serotype Choleraesuis expressing ESBL and fluoroquinolone resistance. The pathogen was supposedly acquired during a trip to Thailand, causing severe fever, cholangitis and pancreatitis. To our knowledge, this is the first report of Salmonella enterica serotype Choleraesuis in Europe expressing such a multidrug resistance pattern. ESBL resistance of Salmonella enterica spp. should be considered in patients with obstructive biliary tract pathology and travel history in endemic countries.
KW  - Biliary physiology
KW  - Infectious disease
KW  - Multidrug resistance
KW  - Primary sclerosing cholangitis
KW  - Salmonella choleraesuis
Y1  - 2017
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/44130
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-441308
SN  - 2219-2840
SN  - 1007-9327
N1  - Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
VL  - 23
IS  - 11
SP  - 2086
EP  - 2089
PB  - WJG Press
CY  - Beijing
ER  -