TY - JOUR A1 - Grösch, Sabine A1 - Alessenko, Alice A1 - Albi, Elisabetta T1 - The many facets of sphingolipids in the specific phases of acute inflammatory response T2 - Mediators of inflammation N2 - This review provides an overview on components of the sphingolipid superfamily, on their localization and metabolism. Information about the sphingolipid biological activity in cell physiopathology is given. Recent studies highlight the role of sphingolipids in inflammatory process. We summarize the emerging data that support the different roles of the sphingolipid members in specific phases of inflammation: (1) migration of immune cells, (2) recognition of exogenous agents, and (3) activation/differentiation of immune cells. Y1 - 2018 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/46967 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-469679 SN - 1466-1861 SN - 0962-9351 N1 - Copyright © 2018 Sabine Grösch et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 27 IS - Art. 5378284 SP - 1 EP - 12 PB - Hindawi Publishing Corp. CY - Sylvania, Ohio ER -