TY - JOUR A1 - Klingelhöfer, Doris A1 - Braun, Markus A1 - Groneberg, Jan David Alexander A1 - Brüggmann, Dörthe T1 - The "forever" per- and polyfluoroalkyl substances (PFAS): a critical accounting of global research on a major threat under changing regulations T2 - Chemosphere N2 - Highlights • Currently, China has the most publications, ahead of the USA and European countries. • Research focuses are strictly separated into ecological and material science topics. • Russia and Ukraine are among the frontrunners with a clear focus on materials science. • The focus in PFAS research is shifting toward ecological issues. • A national imbalance can be observed that leaves the low economies behind. Abstract The European Commission's current efforts to launch the largest proposal to restrict per- and polyfluoroalkyl substances (PFAS) in history reflect the dire global plight of PFAS accumulation in the environment and their health impacts. While there are existing studies on PFAS research, there is a lack of comprehensive analysis that both covers the entire research period and provides deep insights into global research patterns, incentives, and barriers based on various parameters. We have been able to demonstrate the increasing interest in PFAS research, although citation numbers are declining prematurely. Policy regulations based on proving and establishing the toxicity of PFASs have stimulated research in developed countries and vice versa, with increasing emphasis on ecological aspects. China, in particular, is investing increasingly in PFAS research, but without defining or implementing regulations - with devastating effects. The separation of industrial and environmental research interests is clear, with little involvement of developing countries, even though their exposure to PFAS is devastating. It, therefore, requires increased globally networked and multidisciplinary approaches to address PFAS contamination challenges. KW - Water contamination KW - Global networking KW - Persistent organic pollutants KW - PFOA KW - PFOS Y1 - 2024 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/83446 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-834462 SN - 0045-6535 VL - 354 IS - 141694 PB - Elsevier CY - Amsterdam ER -