TY - JOUR A1 - González-González, Ana I. A1 - Schmucker, Christine A1 - Nothacker, Julia A1 - Nguyen, Truc Sophia A1 - Brückle, Maria-Sophie A1 - Blom, Jeanet A1 - Akker, J. M. van den A1 - Röttger, Kristian A1 - Wegwarth, Odette A1 - Hoffmann, Tammy A1 - Gerlach, Ferdinand M. A1 - Straus, Sharon E. A1 - Meerpohl, Jörg J. A1 - Muth, Christiane T1 - End-of-life care preferences of older patients with multimorbidity: protocol of a mixed-methods systematic review T2 - BMJ open N2 - Introduction End-of-life care is an essential task performed by most healthcare providers and often involves decision-making about how and where patients want to receive care. To provide decision support to healthcare professionals and patients in this difficult situation, we will systematically review a knowledge cluster of the end-of-life care preferences of older patients with multimorbidity that we previously identified using an evidence map. Methods and analysis We will systematically search for studies reporting end-of-life care preferences of older patients (mean age ≥60) with multimorbidity (≥2 chronic conditions) in MEDLINE, CINAHL, PsycINFO, Social Sciences Citation Index, Social Sciences Citation Index Expanded, PSYNDEX and The Cochrane Library from inception to September 2019. We will include all primary studies that use quantitative, qualitative and mixed methodologies, irrespective of publication date and language. Two independent reviewers will assess eligibility, extract data and describe evidence in terms of study/population characteristics, preference assessment method and end-of-life care elements that matter to patients (eg, life-sustaining treatments). Risk of bias/applicability of results will be independently assessed by two reviewers using the Mixed-Methods Appraisal Tool. Using a convergent integrated approach on qualitative/quantitative studies, we will synthesise information narratively and, wherever possible, quantitatively. Ethics and dissemination Due to the nature of the proposed systematic review, ethics approval is not required. Results from our research will be disseminated at relevant (inter-)national conferences and via publication in peer-reviewed journals. Synthesising evidence on end-of-life care preferences of older patients with multimorbidity will improve shared decision-making and satisfaction in this final period of life. Y1 - 2020 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/55445 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-554450 SN - 2044-6055 N1 - This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/. VL - 10 IS - 7, art. e038682 SP - 1 EP - 7 PB - BMJ Publishing Group CY - London ER -