TY - JOUR A1 - Gruber-Rouh, Tatjana A1 - Thalhammer, Axel A1 - Klingebiel, Thomas A1 - Mohammed, Nour-Eldin Abdelrehim Nour-Eldin A1 - Vogl, Thomas J. A1 - Eichler, Katrin A1 - Naguib, Nagy Naguib Naeem A1 - Beeres, Martin T1 - Computed tomography-guided biopsies in children : accuracy, efficiency and dose usage T2 - The Italian journal of pediatrics N2 - Background: Computed-tomography-guided interventions are attractive for tissue sampling of paediatric tumor lesions; however, it comes with exposure to ionizing radiation. The aim of this study was to analyse the radiation dose, accuracy and speed of CT-guided interventions in paediatric patient cohort. Methods: We retrospectively reviewed CT-guided interventions over a 10 -year period in 65 children. The intervention site consisted of bones in 38, chest (lung) in 15 and abdomen (liver, lymph nodes) in 12 cases. Radiation dose and duration of the procedures were analysed. The statistical analysis was performed using dedicated statistical software (BiAS 8.3.6 software, Epsilon Verlag, North Hasted). Results: All interventions were performed successfully. Mean target access path to lesion within the patients was 6.0 cm (min 3.5 cm, max 11.2 cm). Time duration to complete intervention was 25:15 min (min 17:03 min, max 43:00 min). The dose-length product (DLP) of intervention scan was 29.5 mGy · cm (min 6 mGy · cm, max 85 mGy · cm) with the lowest dose for biopsies in the region of the chest (p = 0.04). Conclusions: With justified indications, CT-guided paediatric interventions are safe, effective and can be performed both, with short intervention times and low radiation exposure. KW - Biopsy KW - Children KW - CT-guidance Y1 - 2017 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/45266 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-452660 SN - 1824-7288 SN - 1720-8424 SN - 0392-5161 N1 - © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated VL - 43 IS - 1, Art. 4 SP - 1 EP - 6 PB - BioMed Central CY - London ER -