TY  - JOUR
A1  - Blümchen, Katharina
A1  - Fischl, Anna
A1  - Eiwegger, Thomas
A1  - Hamelmann, Eckard
A1  - Klimek, Ludger
A1  - Lange, Lars
A1  - Szépfalusi, Zsolt
A1  - Vogelberg, Christian
A1  - Beyer, Kirsten
T1  - White paper peanut allergy: Part 3: management and therapy of peanut allergy
T2  - Allergo journal international
N2  - The current management of a primary IgE-mediated peanut allergy consists of the two basic pillars “exposure prophylaxis” with avoidance of the allergen and “emergency therapy” with short-term treatment of an acute allergic reaction after accidental ingestion. Accidental reactions are common despite attempted avoidance. The severity of an allergic or even anaphylactic reaction after accidental ingestion is difficult to assess prior to reaction. In addition, reaction thresholds may vary depending on the accompanying augmentation factor. Therefore, every peanut allergic patient should receive individual dietary counseling as well as instructions for the use of the emergency kit and a structured patient education program (anaphylaxis group training), if necessary. For the first time, since fall 2021 a causal treatment option with a drug for oral immunotherapy will now be available for 4‑ to 17-year-old peanut-allergic children and adolescents. The oral immunotherapy with peanut protein as defatted powder of Arachis hypogaea L., semen (peanuts) leads to desensitization with a good efficacy record and an acceptable safety profile. Other treatment options with different therapeutic approaches are also under development and will probably expand the range for treatment in the coming years.
KW  - Allergen avoidance
KW  - Accidental reaction
KW  - Oral immunotherapy
KW  - Epicutaneous immunotherapy
KW  - Anti-IgE
Y1  - 2022
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/69539
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-695399
SN  - 2197-0378
N1  - Open Access funding enabled and organized by Projekt DEAL.
VL  - 31
IS  - 3
SP  - 69
EP  - 80
PB  - Urban & Vogel
CY  - München
ER  -