Self-reported adverse reactions in 4337 healthcare workers immunizations against novel H1N1 influenza

Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic i
Purpose: The use of the 2009 H1N1 vaccine has generated much debate concerning safety issues among the general population and physicians. Therefore, we investigated the safety of an inactivated monovalent H1N1 pandemic influenza vaccine Methods: We focused on the H1N1 pandemic influenza vaccine Pandemrix(R) and applied a self reporting questionnaire in a population of healthcare workers (HCWs) and medical students at a major university hospital. Results: In total, 4337 individuals were vaccinated, consisting of 3808 HCWs and 529 medical students. The vaccination rate of the employees was higher than 40%.The majority of individuals were vaccinated in November 2009. In total, 291 of the 4337 vaccinations were reported to lead to one or more adverse reactions (6.7%). Local reactions were reported in 3.8%, myalgia and arthralgia in 3.7%, fatigue in 3.7%, headache in 3.1%. Conclusions: Our data together with available data from several national and international institutions points to a safe pandemic influenza vaccine.
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Author:Harald Bias, David Quarcoo, Claus Meier-Wronski, Sabine Wicker, Joachim Eberhardt Seybold, Albert Nienhaus, Jan David Alexander Groneberg, Andrés de Roux
URN:urn:nbn:de:hebis:30-113568
DOI:http://dx.doi.org/10.1186/1756-0500-4-297
ISSN:1756-0500
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=21849040
Parent Title (English):BMC Research Notes
Publisher:Biomed Central
Place of publication:London
Document Type:Article
Language:English
Date of Publication (online):2011/09/12
Date of first Publication:2011/08/17
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2011/09/12
Tag:adverse reaction; healthcare worker; immunization; novel H1N1 influenza
Volume:4
Issue:297
Pagenumber:6
First Page:1
Last Page:6
Note:
© 2011 Groneberg et al; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
HeBIS PPN:274964236
Institutes:Medizin
Dewey Decimal Classification:610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 2.0

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