Epimechus curvipes Dietz is designated as type species of the genus Epimechus Dietz. Ten additional species from western North America, including four new species, are assigned to the genus: E. aemulus Fall; E. flavirostris Fall; E. mimicus Dietz; E. adspersus Dietz; E. mobilis Fall; E. nevadicus Dietz; E. molina, new species (Arizona, Baja California Norte); E. combustus, new species (Arizona, New Mexico, Utah); E. signum, new species (Arizona, Coahuila, Colorado, New Mexico, Saskatchewan, Texas, Utah) and E. hesperius, new species (Arizona, California, Colorado, Guanajuato, Idaho, Nevada, New Mexico, Nuevo Leon, South Dakota, Texas, Utah, Wyoming). These are distinguished from other Anthonomini by the short, simple tarsal claws. The names Epimeclws modicus Fall, E. soriculus Dietz, and E. nanulus Fall are placed in new synonymy under E. curvipes. Lectotypes are designated for E. adspersus and E. nevadicus. Two species formerly in Epimechus are transferred the subgenus Cnemocyllus Dietz in Anthonomus Germar: E. arenicolor Fall as Anthonomus arenicolor (Fall), new combination, and E. canoides Fall as Anthonomus canoides (Fall), new combination. Adults of species of Epimechus have been collected on plants in the genera Baccharis, Chrysothamnus, Ericameria, Gutierrezia, Haplopappus, Senecio and Tetradymia (all Asteraceae).