Detecting multineuronal temporal patterns in parallel spike trains
- We present a non-parametric and computationally efficient method that detects spatiotemporal firing patterns and pattern sequences in parallel spike trains and tests whether the observed numbers of repeating patterns and sequences on a given timescale are significantly different from those expected by chance. The method is generally applicable and uncovers coordinated activity with arbitrary precision by comparing it to appropriate surrogate data. The analysis of coherent patterns of spatially and temporally distributed spiking activity on various timescales enables the immediate tracking of diverse qualities of coordinated firing related to neuronal state changes and information processing. We apply the method to simulated data and multineuronal recordings from rat visual cortex and show that it reliably discriminates between data sets with random pattern occurrences and with additional exactly repeating spatiotemporal patterns and pattern sequences. Multineuronal cortical spiking activity appears to be precisely coordinated and exhibits a sequential organization beyond the cell assembly concept.
Author: | Kai S. Gansel, Wolf SingerORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-252022 |
DOI: | https://doi.org/10.3389/fninf.2012.00018 |
ISSN: | 1662-5196 |
Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/22661942 |
Parent Title (English): | Frontiers in neuroinformatics |
Publisher: | Frontiers Research Foundation |
Place of publication: | Lausanne |
Document Type: | Article |
Language: | English |
Date of Publication (online): | 2012/05/22 |
Date of first Publication: | 2012/05/22 |
Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Release Date: | 2012/06/17 |
Tag: | cell assembly; phase sequence; rat visual cortex; spike pattern; synfire braid; synfire chain |
Volume: | 6 |
Issue: | 18 |
Page Number: | 16 |
HeBIS-PPN: | 357451902 |
Institutes: | Wissenschaftliche Zentren und koordinierte Programme / Frankfurt Institute for Advanced Studies (FIAS) |
Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Licence (German): | Creative Commons - Namensnennung 3.0 |