Molecular mechanisms of adaptation of the moderately halophilic bacterium Halobacillis halophilus to its environment
- The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately halophilic bacterium that grows between 0.4 and 3 M NaCl by accumulating both chloride and compatible solutes as osmolytes. Chloride is absolutely essential for growth and, moreover, was shown to modulate gene expression and activity of enzymes involved in osmoadaptation. The synthesis of different compatible solutes is strictly salinity- and growth phase-dependent. This unique hybrid strategy of H. halophilus will be reviewed here taking into account the recently published genome sequence. Based on identified genes we will speculate about possible scenarios of the synthesis of compatible solutes and the uptake of potassium ion which would complete our knowledge of the fine-tuned osmoregulation and intracellular osmolyte balance in H. halophilus.
| Author: | Inga HäneltORCiDGND, Volker MüllerORCiD |
|---|---|
| URN: | urn:nbn:de:hebis:30:3-300100 |
| DOI: | https://doi.org/10.3390/life3010234 |
| ISSN: | 2075-1729 |
| Parent Title (English): | Life |
| Publisher: | MDPI |
| Place of publication: | Basel |
| Document Type: | Article |
| Language: | English |
| Date of Publication (online): | 2013/02/27 |
| Date of first Publication: | 2013/02/27 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Release Date: | 2013/05/23 |
| Tag: | chloride accumulation; compatible solutes; hybrid strategy; osmoadaptation |
| Volume: | 3 |
| Page Number: | 10 |
| First Page: | 234 |
| Last Page: | 243 |
| Note: | © 2013 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
| HeBIS-PPN: | 346675510 |
| Institutes: | Biowissenschaften / Biowissenschaften |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Sammlungen: | Universitätspublikationen |
| Sammlung Biologie / Sondersammelgebiets-Volltexte | |
| Licence (German): |  Creative Commons - Namensnennung 3.0 |
