Analyzing the release of copeptin from the heart in acute myocardial infarction using a transcoronary gradient model

Copeptin is the C-terminal end of pre-provasopressin released equimolar to vasopressin into circulation and recently discussed as promising cardiovascular biomarker amendatory to established markers such as troponins. Va
Copeptin is the C-terminal end of pre-provasopressin released equimolar to vasopressin into circulation and recently discussed as promising cardiovascular biomarker amendatory to established markers such as troponins. Vasopressin is a cytokine synthesized in the hypothalamus. A direct release of copeptin from the heart into the circulation is implied by data from a rat model showing a cardiac origin in hearts put under cardiovascular wall stress. Therefore, evaluation of a potential release of copeptin from the human heart in acute myocardial infarction (AMI) has been done.
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Author:Jes-Niels Boeckel, Jana Oppermann, Remzi Anadol, Stephan Fichtlscherer, Andreas Michael Zeiher, Till Keller
URN:urn:nbn:de:hebis:30:3-425253
DOI:http://dx.doi.org/10.1038/srep20812
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=26864512
Parent Title (English):Scientific Reports
Document Type:Article
Language:English
Date of Publication (online):2016/12/20
Date of first Publication:2016/02/11
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2016/12/21
Volume:6
Issue:20812
Pagenumber:5
First Page:1
Last Page:5
Note:
This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
HeBIS PPN:421524529
Institutes:Medizin
Dewey Decimal Classification:610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0

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