Computed tomography-guided biopsies in children : accuracy, efficiency and dose usage

Background: Computed-tomography-guided interventions are attractive for tissue sampling of paediatric tumor lesions; however, it comes with exposure to ionizing radiation. The aim of this study was to analyse the radiati
Background: Computed-tomography-guided interventions are attractive for tissue sampling of paediatric tumor lesions; however, it comes with exposure to ionizing radiation. The aim of this study was to analyse the radiation dose, accuracy and speed of CT-guided interventions in paediatric patient cohort.
Methods: We retrospectively reviewed CT-guided interventions over a 10 -year period in 65 children. The intervention site consisted of bones in 38, chest (lung) in 15 and abdomen (liver, lymph nodes) in 12 cases. Radiation dose and duration of the procedures were analysed. The statistical analysis was performed using dedicated statistical software (BiAS 8.3.6 software, Epsilon Verlag, North Hasted).
Results: All interventions were performed successfully. Mean target access path to lesion within the patients was 6.0 cm (min 3.5 cm, max 11.2 cm). Time duration to complete intervention was 25:15 min (min 17:03 min, max 43:00 min). The dose-length product (DLP) of intervention scan was 29.5 mGy · cm (min 6 mGy · cm, max 85 mGy · cm) with the lowest dose for biopsies in the region of the chest (p = 0.04).
Conclusions: With justified indications, CT-guided paediatric interventions are safe, effective and can be performed both, with short intervention times and low radiation exposure.
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Metadaten
Author:Tatjana Gruber-Rouh, Axel Thalhammer, Thomas Klingebiel, Nour-Eldin Abdelrehim Nour-Eldin Mohammed, Thomas J. Vogl, Katrin Eichler, Nagy Naguib Naeem Naguib, Martin Beeres
URN:urn:nbn:de:hebis:30:3-452660
DOI:http://dx.doi.org/10.1186/s13052-016-0319-7
ISSN:1824-7288
ISSN:1720-8424
ISSN:0392-5161
Pubmed Id:http://www.ncbi.nlm.nih.gov/pubmed?term=28057068
Parent Title (English):The Italian journal of pediatrics
Publisher:BioMed Central
Place of publication:London
Document Type:Article
Language:English
Year of Completion:2017
Date of first Publication:2017/01/06
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/12/12
Tag:Biopsy; CT-guidance; Children
Volume:43
Issue:1, Art. 4
Pagenumber:6
First Page:1
Last Page:6
Note:
© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated
HeBIS PPN:432101462
Institutes:Medizin
Dewey Decimal Classification:610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0

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