NADPH oxidases: current aspects and tools

  • Reactive oxygen species (ROS) have been shown or at least suggested to play an essential role for cellular signaling as second messengers. NADPH oxidases represent a source of controlled ROS formation. Accordingly, understanding the role of individual NADPH oxidases bears potential to interfere with intracellular signaling cascades without disturbing the signaling itself. Many tools have been developed to study or inhibit the functions and roles of the NADPH oxidases. This short review summarizes diseases, potentially associated with NADPH oxidases, genetically modified animals, and inhibitors.

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Author:Katrin SchröderORCiDGND
URN:urn:nbn:de:hebis:30:3-546595
DOI:https://doi.org/10.1016/j.redox.2020.101512
ISSN:2213-2317
Parent Title (English):Redox Biology
Publisher:Elsevier
Place of publication:Amsterdam [u.a.]
Document Type:Article
Language:English
Date of Publication (online):2020/05/23
Date of first Publication:2020/05/23
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2020/06/12
Volume:27
Issue:101512
Page Number:6
HeBIS-PPN:467349711
Institutes:Medizin / Medizin
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0