Curcumin - a viable agent for better bladder cancer treatment

Although the therapeutic armamentarium for bladder cancer has considerably widened in the last few years, severe side effects and the development of resistance hamper long-term treatment success. Thus, patients turn to na
Although the therapeutic armamentarium for bladder cancer has considerably widened in the last few years, severe side effects and the development of resistance hamper long-term treatment success. Thus, patients turn to natural plant products as alternative or complementary therapeutic options. One of these is curcumin, the principal component of Curcuma longa that has shown chemopreventive effects in experimental cancer models. Clinical and preclinical studies point to its role as a chemosensitizer, and it has been shown to protect organs from toxicity induced by chemotherapy. These properties indicate that curcumin could hold promise as a candidate for additive cancer treatment. This review evaluates the relevance of curcumin as an integral part of therapy for bladder cancer.
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Metadaten
Author:Jochen Rutz, Andrea Janicova, Katja Woidacki, Felix Chun, Roman A. Blaheta, Borna Relja
URN:urn:nbn:de:hebis:30:3-554335
DOI:http://dx.doi.org/10.3390/ijms21113761
ISSN:1422-0067
Parent Title (English):International journal of molecular sciences
Publisher:MDPI
Place of publication:Basel
Document Type:Article
Language:English
Date of Publication (online):2020/05/26
Date of first Publication:2020/05/26
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2020/08/14
Tag:bioavailability; bladder cancer; chemoprotection; chemoresistance; curcumin
Volume:21
Issue:11, art. 3761
Pagenumber:20
First Page:1
Last Page:20
Note:
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
HeBIS PPN:469734043
Institutes:Medizin
Dewey Decimal Classification:610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Open-Access-Publikationsfonds:Medizin
Licence (German):License LogoCreative Commons - Namensnennung 4.0

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