Wirtszellreaktivierung chemisch induzierter Letalschäden im DNS-haltigen Serratia-Phagen Kappa
- After treating free phage Kappa with nitrous acid, triethylenemelamine, ethylmethanesulfonate, or hydroxylamin and using these phages for infecting Serratia H Y wildtype cells, at least 20% of the lethal damage in the phage-DNA can be reactivated by the host ( = host cell reactivation). It is known that all lethal agents tested so far attack the primary structure of the D N A in different ways. Therefore, we assume that the target for the host cell reactivation consists of some damage in the secondary structure of the DNA, because there is probably some coincidence in the action of all agents. The hypothesis that in the DNA changes of thymine are a prerequisite for host cell reactivation has been disproved by the experiments with nitrous acid and ethylmethanesulfonate because both substances do not act on thymine.
| Author: | Ulrich WinklerGND |
|---|---|
| URN: | urn:nbn:de:hebis:30:3-388696 |
| DOI: | https://doi.org/10.1515/znb-1965-0908 |
| ISSN: | 1865-7117 |
| ISSN: | 0932-0776 |
| Parent Title (German): | Zeitschrift für Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie |
| Document Type: | Article |
| Language: | German |
| Date of Publication (online): | 2016/10/24 |
| Year of first Publication: | 1965 |
| Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
| Release Date: | 2016/10/24 |
| Volume: | 20 |
| Issue: | 9 |
| Page Number: | 4 |
| First Page: | 864 |
| Last Page: | 869 |
| Note: | Dieses Werk wurde im Jahr 2013 vom Verlag Zeitschrift für Naturforschung in Zusammenarbeit mit der Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. digitalisiert und unter folgender Lizenz veröffentlicht: Creative Commons Namensnennung-Keine Bearbeitung 3.0 Deutschland Lizenz. |
| HeBIS-PPN: | 399906665 |
| Institutes: | Biowissenschaften / Biowissenschaften |
| Dewey Decimal Classification: | 5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie |
| Sammlungen: | Universitätspublikationen |
| Licence (German): |  Creative Commons - Namensnennung-Keine Bearbeitung |
