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UV-induction of thymine-containing dimers in Saccharomyces cerevisiae

  • In haploid and diploid S. cerevisiae the dimer yield ratio TT̂/CT̂ is found to be 1.2/1 and 1.3/1, resp., at the UV (254 nm) unit dose 1 erg/mm2, the share of TT̂ and CT̂ in a UV (254 nm) lethal hit being 0.7 TT̂ and 0.6 CT̂. A general formulation of the UV lethal hit is given and discussed. The TT̂ + CT̂ yields obtained for S. cerevisiae are compared to those reported for other organisms. It is found that there obviously exists a directly proportional linear correlation between genome size and TT̂ + CT̂ yield for the UV dose range well below the stationary levels of the TT̂ and CT̂ formation kinetics.

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Metadaten
Author:Wolfgang Walter Fäth, Martin BrendelORCiD
URN:urn:nbn:de:hebis:30:3-722345
DOI:https://doi.org/10.1515/znc-1975-11-1221
ISSN:0939-5075
ISSN:1865-7125
Parent Title (German):Zeitschrift für Naturforschung, C
Publisher:Verlag der Zeitschrift für Naturforschung
Place of publication:Tübingen
Document Type:Article
Language:English
Date of Publication (online):2014/06/02
Year of first Publication:1975
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2024/02/02
Tag:Dimer Yield Ratio; Far UV; Kinetics of Dimer Formation
Volume:30.1975
Issue:11-12
Page Number:7
First Page:811
Last Page:817
Institutes:Biowissenschaften
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 57 Biowissenschaften; Biologie / 570 Biowissenschaften; Biologie
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung-Nicht kommerziell-Keine Bearbeitung 3.0