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Proposal of a population wide genome-based testing for Covid-19

  • Our lives (and deaths) have by now been dominated for two years by COVID-19, a pandemic that has caused hundreds of millions of disease cases, millions of deaths, trillions in economic costs, and major restrictions on our freedom. Here we suggest a novel tool for controlling the COVID-19 pandemic. The key element is a method for a population-scale PCR-based testing, applied on a systematic and repeated basis. For this we have developed a low cost, highly sensitive virus-genome-based test. Using Germany as an example, we demonstrate by using a mathematical model, how useful this strategy could have been in controlling the pandemic. We show using real-world examples how this might be implemented on a mass scale and discuss the feasibility of this approach.

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Metadaten
Author:Hans LehrachORCiDGND, Jon CurtisORCiD, Bodo Lange, Lesley A. OgilvieORCiDGND, Richard GaussGND, Christoph SteiningerORCiDGND, Erhard ScholzORCiDGND, Matthias KreckGND
URN:urn:nbn:de:hebis:30:3-736206
DOI:https://doi.org/10.1038/s41598-022-08934-2
ISSN:2045-2322
Parent Title (English):Scientific Reports
Publisher:Macmillan Publishers Limited, part of Springer Nature
Place of publication:London
Document Type:Preprint
Language:English
Date of Publication (online):2022/04/04
Date of first Publication:2022/04/04
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2023/08/02
Volume:12
Issue:5618
Page Number:8
HeBIS-PPN:51064600X
Institutes:Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0