Left ventricular non-compaction cardiomyopathy and left ventricular assist device: a word of caution

  • BACKGROUND: In patients with left ventricular non-compaction (LVNC), implantation of a left ventricular assist device (LVAD) may be performed as a bridge to transplantation. In this respect, the particular characteristics of the left ventricular myocardium may represent a challenge. CASE PRESENTATION: We report a patient with LVNC who required urgent heart transplantation for inflow cannula obstruction nine months after receiving a LVAD. LVAD parameters, echocardiography and examination of the explanted heart suggested changes of left ventricular configuration brought about by LVAD support as the most likely cause of inflow cannula obstruction. CONCLUSIONS: We conclude that changes experienced by non-compacted myocardium during LVAD support may give rise to inflow cannula obstruction and flow reduction. Presence of LVNC mandates tight surveillance for changes in LV configuration and LVAD flow characteristics and may justify urgent transplantation listing status.

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Author:Angela KornbergerORCiDGND, Ulrich Alfred StockORCiDGND, Petar RisteskiORCiDGND, Andrés Beiras FernándezGND
URN:urn:nbn:de:hebis:30:3-306470
DOI:https://doi.org/10.1186/s13019-016-0503-2
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/27422642
Parent Title (English):Journal of cardiothoracic surgery
Publisher:BioMed Central
Place of publication:London
Document Type:Article
Language:English
Year of Completion:2016
Year of first Publication:2016
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/01/30
Tag:Heart transplantation; Inflow obstruction; Left ventricular assist device; Left ventricular non-compaction,
Volume:11
Issue:108
Page Number:5
Note:
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
HeBIS-PPN:423914715
Institutes:Medizin / Medizin
Dewey Decimal Classification:6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 4.0