Oliver Blanck, Laura Masi, Mark K. H. Chan, Sebastian Adamczyk, Christian Albrecht, Marie-Christin Damme, Britta Loutfi-Krauss, Manfred Alraun, Roman Fehr, Ulla Ramm, Frank-Andre Siebert, Tenzin Sonam Stelljes, Daniela Poppinga, Björn Poppe
- Purpose: High precision radiosurgery demands comprehensive delivery-quality-assurance techniques. The use of a liquid-filled ion-chamber-array for robotic-radiosurgery delivery-quality-assurance was investigated and validated using several test scenarios and routine patient plans.
Methods and material: Preliminary evaluation consisted of beam profile validation and analysis of source–detector-distance and beam-incidence-angle response dependence. The delivery-quality-assurance analysis is performed in four steps: (1) Array-to-plan registration, (2) Evaluation with standard Gamma-Index criteria (local-dose-difference ⩽ 2%, distance-to-agreement ⩽ 2 mm, pass-rate ⩾ 90%), (3) Dose profile alignment and dose distribution shift until maximum pass-rate is found, and (4) Final evaluation with 1 mm distance-to-agreement criterion. Test scenarios consisted of intended phantom misalignments, dose miscalibrations, and undelivered Monitor Units. Preliminary method validation was performed on 55 clinical plans in five institutions.
Results: The 1000SRS profile measurements showed sufficient agreement compared with a microDiamond detector for all collimator sizes. The relative response changes can be up to 2.2% per 10 cm source–detector-distance change, but remains within 1% for the clinically relevant source–detector-distance range. Planned and measured dose under different beam-incidence-angles showed deviations below 1% for angles between 0° and 80°. Small-intended errors were detected by 1 mm distance-to-agreement criterion while 2 mm criteria failed to reveal some of these deviations. All analyzed delivery-quality-assurance clinical patient plans were within our tight tolerance criteria.
Conclusion: We demonstrated that a high-resolution liquid-filled ion-chamber-array can be suitable for robotic radiosurgery delivery-quality-assurance and that small errors can be detected with tight distance-to-agreement criterion. Further improvement may come from beam specific correction for incidence angle and source–detector-distance response.
MetadatenAuthor: | Oliver BlanckORCiDGND, Laura Masi, Mark K. H. Chan, Sebastian Adamczyk, Christian Albrecht, Marie-Christin Damme, Britta Loutfi-Krauss, Manfred Alraun, Roman Fehr, Ulla Ramm, Frank-Andre Siebert, Tenzin Sonam Stelljes, Daniela Poppinga, Björn Poppe |
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URN: | urn:nbn:de:hebis:30:3-427542 |
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DOI: | https://doi.org/10.1016/j.ejmp.2016.05.060 |
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ISSN: | 1120-1797 |
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ISSN: | 1724-191X |
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Pubmed Id: | https://pubmed.ncbi.nlm.nih.gov/27245301 |
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Parent Title (English): | Physica medica |
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Publisher: | Elsevier |
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Place of publication: | Amsterdam [u. a.] |
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Document Type: | Article |
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Language: | English |
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Date of Publication (online): | 2017/04/27 |
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Year of first Publication: | 2016 |
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Publishing Institution: | Universitätsbibliothek Johann Christian Senckenberg |
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Release Date: | 2017/04/27 |
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Tag: | CyberKnife robotic radiosurgery; Delivery quality assurance; Liquid filled MicroLion ion chamber array; Stereotactic body radiation therapy |
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Volume: | 32 |
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Issue: | 6 |
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Page Number: | 9 |
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First Page: | 838 |
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Last Page: | 846 |
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Note: | © 2016 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
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HeBIS-PPN: | 428738125 |
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Institutes: | Medizin / Medizin |
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Dewey Decimal Classification: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
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Sammlungen: | Universitätspublikationen |
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Licence (English): | Creative Commons - Namensnennung-Nicht kommerziell 4.0 |
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