Proteo-lipobeads for the oriented encapsulation of membrane proteins

  • As a surrogate of live cells, proteo-lipobeads are presented, encapsulating functional membrane proteins in a strict orientation into a lipid bilayer. Assays can be performed just as on live cells, for example using fluorescence measurements. As a proof of concept, we have demonstrated proton transport through cytochrome c oxidase.

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Author:Pinar Frank, Bernhard Siebenhofer, Theresa Hanzer, Andreas F. Geiss, Florian Schadauer, Ciril Reiner-Rozman, Bill Durham, Leslie M. Loew, Bernd LudwigGND, Oliver-Matthias H. Richter, Christoph Nowak, Renate L. C. Naumann
URN:urn:nbn:de:hebis:30:3-446983
DOI:https://doi.org/10.1039/C4SM02646B
ISSN:1744-6848
ISSN:1744-683X
Pubmed Id:https://pubmed.ncbi.nlm.nih.gov/25763882
Parent Title (English):Soft matter
Publisher:Royal Soc. of Chemistry
Place of publication:London
Document Type:Article
Language:English
Year of Completion:2015
Date of first Publication:2015/03/02
Publishing Institution:Universitätsbibliothek Johann Christian Senckenberg
Release Date:2017/12/21
Volume:11
Issue:15
Page Number:3
First Page:2906
Last Page:2908
Note:
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
HeBIS-PPN:430465351
Institutes:Biochemie, Chemie und Pharmazie / Biochemie und Chemie
Dewey Decimal Classification:5 Naturwissenschaften und Mathematik / 54 Chemie / 540 Chemie und zugeordnete Wissenschaften
Sammlungen:Universitätspublikationen
Licence (German):License LogoCreative Commons - Namensnennung 3.0