Impact of DMEK on visual quality in patients with Fuchs' endothelial dystrophy
- Purpose: To investigate short-term (3 months follow-up) changes in visual quality following Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED). Methods: In this prospective institutional case series, 51 patients that underwent DMEK for FED were included. Assessment included the Quality of Vision (QoV) questionnaire preoperatively, at 1 month, and 3 months after surgery. Secondary outcome measures were anterior segment parameters acquired by Scheimpflug imaging, corrected distance visual acuity (CDVA), and endothelial cell density (ECD). Results: Glare, hazy vision, blurred vision, and daily fluctuation in vision were the symptoms mostly reported preoperatively. All symptoms demonstrated a significant reduction of item scores for severity, frequency, and bothersome in the course after DMEK (P < 0.01). Glare and fluctuation in vision remained to some extent during the follow-up period (median score = 1). Preoperatively, corneal densitometry correlated moderately to weakly with severity of hazy vision (rs = 0.39; P = 0.03) and frequency (rs = 0.26; P = 0.02) as well as severity (rs = 0.27; P = 0.03) of blurry vision. CDVA and central corneal thickness (CCT) did not correlate with visual complains. Conclusions: Following DMEK for FED, patient-reported visual symptoms assessed by the QoV questionnaire represent a useful tool providing valuable information on the impact of DMEK on visual quality that cannot be directly estimated by morphological parameters and visual acuity only.
Verfasserangaben: | Vanessa Ademmer, Bishr AghaGND, Mehdi ShajariGND, Thomas KohnenORCiDGND, Ingo SchmackORCiDGND |
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URN: | urn:nbn:de:hebis:30:3-634724 |
DOI: | https://doi.org/10.1007/s00417-021-05334-6 |
ISSN: | 1435-702X |
Titel des übergeordneten Werkes (Englisch): | Graefe's archive for clinical and experimental ophthalmology |
Verlag: | Springer |
Verlagsort: | Berlin ; Heidelberg |
Dokumentart: | Wissenschaftlicher Artikel |
Sprache: | Englisch |
Datum der Veröffentlichung (online): | 16.09.2021 |
Datum der Erstveröffentlichung: | 16.09.2021 |
Veröffentlichende Institution: | Universitätsbibliothek Johann Christian Senckenberg |
Datum der Freischaltung: | 09.02.2022 |
Freies Schlagwort / Tag: | DMEK; Fuchs endothelial dystrophy; Scheimpflug imaging; Visual quality |
Jahrgang: | 260 |
Seitenzahl: | 8 |
Erste Seite: | 521 |
Letzte Seite: | 528 |
HeBIS-PPN: | 491727488 |
Institute: | Medizin / Medizin |
DDC-Klassifikation: | 6 Technik, Medizin, angewandte Wissenschaften / 61 Medizin und Gesundheit / 610 Medizin und Gesundheit |
Sammlungen: | Universitätspublikationen |
Lizenz (Deutsch): | ![]() |