TY - INPR A1 - Parra-Rojas, César A1 - Hernández-Vargas, Esteban A. T1 - PDEparams: Parameter fitting toolbox for partial differential equations in Python T2 - bioRxiv N2 - Motivation: Partial differential equations (PDEs) is a well-established and powerful tool to simulate multi-cellular biological systems. However, available free tools for validation against data are not established. The PDEparams module provides flexible functionality in Python for parameter estimation in PDE models. Results: The PDEparams module provides a flexible interface and readily accommodates different parameter analysis tools in PDE models such as computation of likelihood profiles, and parametric boot-strapping, along with direct visualisation of the results. To our knowledge, it is the first open, freely available tool for parameter fitting of PDE models. Availability and implementation: The PDEparams module is distributed under the MIT license. The source code, usage instructions and step-by-step examples are freely available on GitHub at github.com/systemsmedicine/PDE_params. Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/70067 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-700679 IS - 631226 ER -