Refine
Year of publication
Document Type
- Article (30440) (remove)
Language
- English (15150)
- German (13284)
- Portuguese (696)
- French (387)
- Croatian (251)
- Spanish (250)
- Italian (132)
- Turkish (113)
- Multiple languages (36)
- Latin (35)
Has Fulltext
- yes (30440)
Keywords
- Deutsch (503)
- taxonomy (420)
- Literatur (297)
- Hofmannsthal, Hugo von (185)
- Rezeption (178)
- new species (178)
- Übersetzung (163)
- Filmmusik (155)
- Johann Wolfgang von Goethe (131)
- Vormärz (113)
Institute
- Medizin (5097)
- Physik (1726)
- Extern (1108)
- Biowissenschaften (1100)
- Biochemie und Chemie (1091)
- Gesellschaftswissenschaften (798)
- Frankfurt Institute for Advanced Studies (FIAS) (696)
- Geowissenschaften (582)
- Präsidium (453)
- Philosophie (448)
Herbert Marcuse es considerado, sin lugar a dudas, como el máximo exponente y punto culminante de la Teoría Crítica, la teoría empleada por la llamada Escuela de Frankfurt.1La Escuela de Frankfurt es el término con el que se conoce a un grupo de hombres interesados en teoría social y formados en escuelas diferentes, pero que comparten la idea de retomar el marxismo con el propósito de elaborar una crítica de la sociedad existente, a partir de distintas disciplinas. A la Escuela de Frankfurt, conocida inicialmente como Instituto de Investigación Social, pertenecen pensadores como Herbert Marcuse, Erich Fromm, Max Horkheimer, Theodor Adorno, Leo 54Rosendo Bolívar Meza Lowenthal, Friedrich Pollok, Franz Newmann, Jurgen Habermas, Walter Ben-jamin, Karl August Wittfogel, Sorge,Grossmann, Félix J. Weil y otros.
Bei der Durchsicht von literarischen und literarkritischen Werken der 1830er und 40er Jahre wird schnell deutlich, daß jedes einen anderen 'Goethe' hat. Damit ist nicht nur den Tatsachen Rechnung getragen, daß jeder der Autoren seine ganz individuelle Sicht auf Goethe zur Geltung bringen will - um des eignen Profils und der Distinktionsgewinne willen - und daß jede der sich ausdifferenzierenden ideologischen Positionen,
die dem Vormärz sein besonderes Gepräge geben, sich ihre spezielle, pejorative oder verklärende Mystifikation zurechtlegt.
Primary breast lymphoma accounts for 0.04%-0.5% of all breast malignancies. Primary non-Hodgkin’s lymphomas of the breast are extremely rare and represent approximately 0.38%-0.7% of all cases. Epstein-Barr virus (EBV) has been postulated to play an important role in the pathogenesis of Hodgkin’s lymphoma. We present a case of EBV-positive primary Hodgkin’s lymphoma of the breast. Although there is no sufficient data on this challenging diagnosis, it is known that it could be misdiagnosed with inflammatory breast carcinoma. A crucial part of the proper histopathologic diagnosis is immunohistochemistry. Different modalities of treatment include operative procedure, chemotherapy and radiotherapy. Recent studies suggest chemotherapy and radiotherapy to be initial treatment for patients with primary breast lymphomas.
In the fish embryo toxicity (FET) test with zebrafish (Danio rerio) embryos, 3,4-dichloroaniline (3,4-DCA) is often employed as a positive control substance. Previous studies have characterized bioconcentration and transformation of 3,4-DCA in this test under flow-through conditions. However, the dynamic changes of chemical concentrations in exposure media and embryos were not studied systematically under the commonly used semi-static exposure conditions in multiwell plates. To overcome these limitations, we conducted semi-static exposures experiments where embryolarval zebrafish were exposed to 0.5, 2.0, and 4.0 mg L−1 of 3,4-DCA for up to 120 hpf, with 24-h renewal intervals. During each renewal interval, concentrations of 3,4-DCA were quantified in water samples at 0, 6, 18, and 24 h using high-performance liquid chromatography with diode array detection. Levels of 3,4-DCA in larvae were measured after 120 h exposure. Concentrations of 3,4-DCA in the test vessels decreased rapidly during exposure. Taking these dynamics into account, bioconcentration factors in the present study ranged from 12.9 to 29.8 L kg−1, depending on exposure concentration. In summary, this study contributed to our knowledge of chemical dynamics in the FET test with embryolarval zebrafish, which will aid in defining suitable exposure conditions for future studies.
Drug resistance of childhood cancer neuroblastoma is a serious clinical problem. Patients with relapsed disease have a poor prognosis despite intense treatment. In the present study, we aimed to identify chemoresistance gene expression signatures in vincristine resistant neuroblastoma cells. We found that vincristine-resistant neuroblastoma cells formed larger clones and survived under reduced serum conditions as compared with non-resistant parental cells. To identify the possible mechanisms underlying vincristine resistance in neuroblastoma cells, we investigated the expression profiles of genes known to be involved in cancer drug resistance. This specific gene expression patterns could predict the behavior of a tumor in response to chemotherapy and for predicting the prognosis of high-risk neuroblastoma patients. Our signature could help chemoresistant neuroblastoma patients in avoiding useless and harmful chemotherapy cycles.
Our primary objective is to construct a plausible, unified model of inflation, dark energy and dark matter from a fundamental Lagrangian action first principle, wherein all fundamental ingredients are systematically dynamically generated starting from a very simple model of modified gravity interacting with a single scalar field employing the formalism of non-Riemannian spacetime volume-elements. The non-Riemannian volume element in the initial scalar field action leads to a hidden, nonlinear Noether symmetry which produces an energy-momentum tensor identified as the sum of a dynamically generated cosmological constant and dust-like dark matter. The non-Riemannian volume-element in the initial Einstein–Hilbert action upon passage to the physical Einstein-frame creates, dynamically, a second scalar field with a non-trivial inflationary potential and with an additional interaction with the dynamically generated dark matter. The resulting Einstein-frame action describes a fully dynamically generated inflationary model coupled to dark matter. Numerical results for observables such as the scalar power spectral index and the tensor-to-scalar ratio conform to the latest 2018 PLANCK data.
Our knowledge of early evolution of snakes is improving, but all that we can infer about the evolution of modern clades of snakes such as boas (Booidea) is still based on isolated bones. Here, we resolve the phylogenetic relationships of Eoconstrictor fischeri comb. nov. and other booids from the early-middle Eocene of Messel (Germany), the best-known fossil snake assemblage yet discovered. Our combined analyses demonstrate an affinity of Eoconstrictor with Neotropical boas, thus entailing a South America-to-Europe dispersal event. Other booid species from Messel are related to different New World clades, reinforcing the cosmopolitan nature of the Messel booid fauna. Our analyses indicate that Eoconstrictor was a terrestrial, medium- to large-bodied snake that bore labial pit organs in the upper jaw, the earliest evidence that the visual system in snakes incorporated the infrared spectrum. Evaluation of the known palaeobiology of Eoconstrictor provides no evidence that pit organs played a role in the predator–prey relations of this stem boid. At the same time, the morphological diversity of Messel booids reflects the occupation of several terrestrial macrohabitats, and even in the earliest booid community the relation between pit organs and body size is similar to that seen in booids today.