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Background; Salivary gland carcinomas (SGC) cover a heterogeneous group of malignancies with a lack of data of high-level evidence.
Methods; Clinical data of 127 patients treated for SGC at a university cancer center between 2002 and 2017 were analyzed retrospectively. The association of clinicopathological characteristics, treatment modalities, adverse events, and outcome was assessed.
Results: Patients received surgery (n = 65), surgery followed by (chemo-)radiotherapy (n = 56), or primary (chemo-)radiotherapy (n = 6). Injury to the cranial nerves or their branches was the most frequent surgical complication affecting 40 patients (33.1%). Ten year overall and progression-free survival rates were 73.2% and 65.4%, respectively. Parotid tumor site, advanced tumor, and positive nodal stage remained independent negative prognostic factors for overall survival, loco-regional and distant tumor control in multivariate analysis.
Conclusions: Optimizing treatment strategies for SGC, depending on distinct clinicopathological factors, remains challenging due to the low incidence rates of the disease.
"Hock war ganz nett; auch klug; relativ ehrlich; im ganzen steht er mir mit Hochschätzung gegenüber, die durch Germanistik und Renegatentum erheblich beeinträchtigt wird" - Arthur Schnitzler, Tagebuch 15/12/1920
Schnitzler hatte mit Germanisten nicht immer Glück, vielleicht gründet von da her seine Skepsis gegenüber der Zunft. Und wenn man sich genauer ansieht, was nachgeborene Germanisten und Editoren manchmal mit dem angestellt haben, was er geschrieben hat, ist man geneigt, diesem absprechenden Urteil beizustimmen.