TY - JOUR A1 - Niederberger, Ellen A1 - Parnham, Michael J. A1 - Maas, Jochen A1 - Geisslinger, Gerd T1 - 4 Ds in health research-working together toward rapid precision medicine T2 - EMBO molecular medicine N2 - Patient therapy is based mainly on a combination of diagnosis, suitable monitoring or support devices and drug treatment and is usually employed for a pre-existing disease condition. Therapy remains predominantly symptom-based, although it is increasingly clear that individual treatment is possible and beneficial. However, reasonable precision medicine can only be realized with the coordinated use of diagnostics, devices and drugs in combination with extensive databases (4Ds), an approach that has not yet found sufficient implementation. The practical combination of 4Ds in health care is progressing, but several obstacles still hamper their extended use in precision medicine. KW - Biomarkers & Diagnostic Imaging KW - Metabolism Y1 - 2019 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/53426 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-534261 SN - 1757-4684 SN - 1715-4684 N1 - © 2019 The Authors. Published under the terms of the CC BY 4.0 license. VL - 11 IS - 11, e10917 SP - 1 EP - 7 PB - Wiley-VCH ; EMBO Press CY - Weinheim ; Heidelberg ER -