TY  - JOUR
A1  - Mader, Oscar Maximilian
A1  - Farivar Tanha, Nadine
A1  - Mader, Felix Hans Alexander
A1  - Happel, Christian
A1  - Korkusuz, Yücel
A1  - Grünwald, Frank
T1  - Comparative study evaluating the efficiency of cooled and uncooled single-treatment MWA in thyroid nodules after a 3-month follow up
T2  - European journal of radiology open
N2  - Objective: The aim of this study was to evaluate and compare the efficacy of single-treatment cooled and uncooled microwave ablation in thyroid nodules.
Methods: Eighteen patients (11 women) with an average age of 62 years (range: 41–80) with 18 cold, mainly solid or solid thyroid nodules were treated with cooled or uncooled microwave ablation. Pain during the treatment was measured on a 10-point score. Side effects revealed by ultrasound or patients’ complaints were documented. Laboratory data was evaluated before, 24 h and three months after MWA. Nodule volumes were measured before and three months after MWA.
Results: Cooled MWA was better tolerated than uncooled MWA. A significant reduction of thyroid nodule volume was observed in all cases. The reduction after cMWA was higher (40%) than after uMWA (29%). Pain intensity during cMWA was significantly lower than after uMWA. CMWA and uMWA led to a significant decrease of nodule blood circulation and echogenicity and to a significant increase of nodule elasticity. Thyroid function remained intact in all cases. The energy (kJ/s) administered into the nodules in relation to the ablation time during cMWA was higher than during uMWA.
Conclusions: CMWA leads to a slightly higher but statistically not significant nodule volume reduction than uMWA. Patient comfort during cMWA is higher than during uMWA. The risk of unintended side effects is less in cMWA. A Single-treatment provides sufficient results.
KW  - Microwave ablation
KW  - Volume reduction of thyroid nodules
KW  - Single-treatment
KW  - Pain scale MWA
Y1  - 2017
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/77338
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-773381
SN  - 2352-0477
VL  - 4
SP  - 4
EP  - 8
PB  - Elsevier
CY  - Amsterdam
ER  -