TY  - JOUR
A1  - Baldofski, Sabrina
A1  - Mauche, Nicole
A1  - Dogan-Sander, Ezgi
A1  - Bot, Mariska
A1  - Brouwer, Ingeborg Annemarie
A1  - Paans, Nadine P. G.
A1  - Cabout, Mieke
A1  - Gili, Margarita
A1  - Grootheest, Gerard van
A1  - Hegerl, Ulrich
A1  - Owens, Matthew
A1  - Roca, Miquel
A1  - Visser, Marjolein
A1  - Watkins, Ed
A1  - Penninx, Brenda W. J. H.
A1  - Kohls, Elisabeth
T1  - Depressive symptom clusters in relation to body weight status: Results from two large European multicenter studies
T2  - Frontiers in psychiatry
N2  - Background: There is strong evidence for a bidirectional association between depression and obesity. Several biological, psychological, and behavior-related factors may influence this complex association. Clinical impression and preliminary evidence suggest that patients with a diagnosis of major depressive disorder may endorse very different depressive symptom patterns depending on their body weight status. Until now, little is known about potential differences in depressive symptoms in relation to body weight status.
Objective: The aim of this analysis is the investigation of potential differences in depressive symptom clusters (mood symptoms, somatic/vegetative symptoms, and cognitive symptoms) in relation to body weight status.
Methods: Cross-sectional baseline data were derived from two large European multicenter studies: the MooDFOOD Trial and the NESDA cohort study, including persons with overweight and obesity and normal weight reporting subthreshold depressive symptoms (assessment via Inventory of Depressive Symptomatology Self-Report, IDS-SR30). Different measures for body weight status [waist-to-hip ratio (WHR) and body mass index (BMI)] were examined. Propensity score matching was performed and multiple linear regression analyses were conducted.
Results: A total of n = 504 individuals (73.0% women) were analyzed. Results show that more somatic/vegetative depressive symptoms, such as pain, change in appetite and weight, gastrointestinal symptoms, and arousal-related symptoms, were significantly associated with both a higher BMI and higher WHR, respectively. In addition, being male and older age were significantly associated with higher WHR. Mood and cognitive depressive symptoms did not yield significant associations for both body weight status measures.
Conclusions: Somatic/vegetative symptoms and not mood and cognitive symptoms of depression are associated with body weight status. Thus, the results support previous findings of heterogeneous depressive symptoms in relation to body weight status. In addition to BMI, other body weight status measures for obesity should be taken into account in future studies.
Clinical Trial Registration:www.ClinicalTrials.gov, identifier NCT02529423.
KW  - depression
KW  - depressive symptoms
KW  - obesity
KW  - overweight
KW  - body mass index
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/51846
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-518467
SN  - 1664-0640
N1  - Copyright © 2019 Baldofski, Mauche, Dogan-Sander, Bot, Brouwer, Paans, Cabout, Gili, van Grootheest, Hegerl, Owens, Roca, Visser, Watkins, Penninx and Kohls. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
VL  - 10
IS  - Art. 858
SP  - 1
EP  - 8
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  -