TY  - JOUR
A1  - Ratka, Christoph Martin
A1  - Weigl, Paul
A1  - Henrich, Dirk
A1  - Koch, Felix
A1  - Schlee, Markus
A1  - Zipprich, Holger
T1  - The effect of in vitro electrolytic cleaning on biofilm-contaminated implant surfaces
T2  - Journal of Clinical Medicine
N2  - Purpose: Bacterial biofilms are a major problem in the treatment of infected dental and orthopedic implants. The purpose of this study is to investigate the cleaning effect of an electrolytic approach (EC) compared to a powder-spray system (PSS) on titanium surfaces. Materials and Methods: The tested implants (different surfaces and alloys) were collated into six groups and treated ether with EC or PSS. After a mature biofilm was established, the implants were treated, immersed in a nutritional solution, and streaked on Columbia agar. Colony-forming units (CFUs) were counted after breeding and testing (EC), and control (PSS) groups were compared using a paired sample t-test. Results: No bacterial growth was observed in the EC groups. After thinning to 1:1,000,000, 258.1 ± 19.9 (group 2), 264.4 ± 36.5 (group 4), and 245.3 ± 40.7 (group 6) CFUs could be counted in the PSS groups. The difference between the electrolytic approach (test groups 1, 3, and 5) and PSS (control groups 2, 4, and 6) was statistically extremely significant (p-value < 2.2 × 10−16). Conclusion: Only EC inactivated the bacterial biofilm, and PSS left reproducible bacteria behind. Within the limits of this in vitro test, clinical relevance could be demonstrated.
KW  - dental implant
KW  - biofilm
KW  - infection
KW  - perio-prosthetic joint infection
KW  - periimplantitis
KW  - electrolytic cleaning
Y1  - 2019
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/51514
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-515148
SN  - 2077-0383
N1  - This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
VL  - 8
IS  - 9, Art. 1397
SP  - 1
EP  - 13
PB  - MDPI
CY  - Basel
ER  -