TY - JOUR A1 - Scichilone, Nicola A1 - Barnes, John A1 - Battaglia, Salvatore A1 - Benfante, Alida A1 - Brown, Robert A1 - Canonica, Giorgio Walter A1 - Caramori, Gaetano A1 - Cazzola, Mario A1 - Centanni, Stefano A1 - Cianferoni, Antonella A1 - Corsico, Angelo A1 - De Carlo, Giuseppe A1 - Di Marco, Fabiano A1 - Gaga, Mina A1 - Hawrylowicz, Catherine A1 - Heffler, Enrico A1 - Matera, Maria Gabriella A1 - Matucci, Andrea A1 - Paggiaro, Pierluigi A1 - Papi, Alberto A1 - Popov, Todor A1 - Rogliani, Paola A1 - Santus, Pierachille A1 - Solidoro, Paolo A1 - Togias, Alkis A1 - Boulet, Louis-Philippe T1 - The hidden burden of severe asthma: from patient perspective to new opportunities for clinicians T2 - Journal of clinical medicine N2 - Severe asthma is an important topic in respiratory diseases, due to its high impact on morbidity and mortality as well as on health-care resources. The many challenges that still exist in the management of the most difficult-to-treat forms of the disease, and the acknowledgement of the existence of unexplored areas in the pathophysiological mechanisms and the therapeutic targets represent an opportunity to gather experts in the field with the immediate goals to summarize current understanding about the natural history of severe asthma and to identify gaps in knowledge and research opportunities, with the aim to contribute to improved medical care and health outcomes. This article is a consensus document from the “International Course on Severe Asthma” that took place in Palermo, Italy, on May 10–11, 2019. Emerging topics in severe asthma were addressed and discussed among experts, with special focus on patient’s needs and research opportunities, with the aim to highlight the unanswered questions in the diagnostic process and therapeutic approach. KW - severe asthma KW - precision medicine KW - biomarkers KW - patient’s perspective Y1 - 2020 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/56539 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-565397 SN - 2077-0383 VL - 9 IS - article 2397 PB - MDPI CY - Basel ER -