TY - JOUR A1 - Reber, Stefan Oskar A1 - Slattery, David A. T1 - Editorial: Using stress-based animal models to understand the mechanisms underlying psychiatric and somatic disorders T2 - Frontiers in psychiatry N2 - Chronic or repeated stress, particularly psychosocial stress, is an acknowledged risk factor for numerous affective and somatic disorders in modern societies. Thus, there is substantial evidence showing that chronic stress can increase the likelihood of major depressive disorder and anxiety disorders, as well as cardiovascular diseases, irritable bowel syndrome and pain syndromes, to name but a few, in vulnerable individuals. Although a number of pharmacological agents are available to treat such stress-related disorders, many patients do not respond to them, and those who do often report a number of side effects. ... KW - stress KW - microbiome KW - animal models KW - glucocorticoids KW - prefrontal cortex KW - behavior KW - irritable bowel syndrome Y1 - 2016 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/51897 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-518978 SN - 1664-0640 N1 - Copyright: © 2016 Reber and Slattery. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. VL - 7 IS - Art. 192 SP - 1 EP - 2 PB - Frontiers Research Foundation CY - Lausanne ER -