TY - JOUR A1 - Stöver, Timo A1 - Lenarz, Thomas T1 - Biomaterials in cochlear implants T2 - GMS Current topics in otorhinolaryngology - head and neck surgery N2 - The cochlear implant (CI) represents, for almost 25 years now, the gold standard in the treatment of children born deaf and for postlingually deafened adults. These devices thus constitute the greatest success story in the field of ‘neurobionic’ prostheses. Their (now routine) fitting in adults, and especially in young children and even babies, places exacting demands on these implants, particularly with regard to the biocompatibility of a CI’s surface components. Furthermore, certain parts of the implant face considerable mechanical challenges, such as the need for the electrode array to be flexible and resistant to breakage, and for the implant casing to be able to withstand external forces. As these implants are in the immediate vicinity of the middle-ear mucosa and of the junction to the perilymph of the cochlea, the risk exists – at least in principle – that bacteria may spread along the electrode array into the cochlea. The wide-ranging requirements made of the CI in terms of biocompatibility and the electrode mechanism mean that there is still further scope – despite the fact that CIs are already technically highly sophisticated – for ongoing improvements to the properties of these implants and their constituent materials, thus enhancing the effectiveness of these devices. This paper will therefore discuss fundamental material aspects of CIs as well as the potential for their future development. Keywords: cochlear implant, biomaterials, biocompatibility, electrode, inner ear, cochleostomy, surface functionalization, drug delivery, nanoparticles, coating Y1 - 2011 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/22539 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30-113945 SN - 1865-1011 N1 - © 2011 Stöver et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free: to Share – to copy, distribute and transmit the work, provided the original author and source are credited. VL - 8 IS - Doc10 SP - 1 EP - 22 PB - gms CY - Düsseldorf ER -