TY - JOUR A1 - Casanova Soberón, Adrián González A1 - Kurt, Noemi A1 - Pérez, José Luis T1 - The ancestral selection graph for a Λ-asymmetric Moran model T2 - Theoretical population biology N2 - Motivated by the question of the impact of selective advantage in populations with skewed reproduction mechanisms, we study a Moran model with selection. We assume that there are two types of individuals, where the reproductive success of one type is larger than the other. The higher reproductive success may stem from either more frequent reproduction, or from larger numbers of offspring, and is encoded in a measure Λ for each of the two types. Λ-reproduction here means that a whole fraction of the population is replaced at a reproductive event. Our approach consists of constructing a Λ-asymmetric Moran model in which individuals of the two populations compete, rather than considering a Moran model for each population. Provided the measure are ordered stochastically, we can couple them. This allows us to construct the central object of this paper, the Λ−asymmetric ancestral selection graph, leading to a pathwise duality of the forward in time Λ-asymmetric Moran model with its ancestral process. We apply the ancestral selection graph in order to obtain scaling limits of the forward and backward processes, and note that the frequency process converges to the solution of an SDE with discontinuous paths. Finally, we derive a Griffiths representation for the generator of the SDE and use it to find a semi-explicit formula for the probability of fixation of the less beneficial of the two types. KW - Moran model KW - Ancestral selection graph KW - Duality KW - Λ-coalescent KW - Fixation probability Y1 - 2024 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/83472 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-834722 SN - 0040-5809 VL - 2024 IS - In Press, Corrected Proof PB - Elsevier CY - Amsterdam ER -