TY  - JOUR
A1  - Fulda, Simone
T1  - Redox regulation of Smac mimetic-induced cell death
T2  - Molecular & cellular oncology
N2  - Cell death and survival programs are controlled by the cellular redox state, which is typically dysregulated during oncogenesis. A recent study reports that the inhibition of antioxidant defenses resulting from glutathione depletion can prime acute lymphoblastic leukemia cells for death induced by Smac mimetics.
KW  - apoptosis
KW  - Smac
KW  - leukemia
KW  - redox
KW  - cell death
Y1  - 2015
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/50673
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-506739
SN  - 2372-3556
N1  - This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.
VL  - 2
IS  - 4
SP  - e1000697-1
EP  - e1000697-2
PB  - Taylor & Francis
CY  - London
ER  -