TY  - JOUR
A1  - Holder, Jana
A1  - Drongelen, Stefan van
A1  - Uhlrich, Scott David
A1  - Herrmann, Eva
A1  - Meurer, Andrea
A1  - Stief, Felix
T1  - Peak knee joint moments accurately predict medial and lateral knee contact forces in patients with valgus malalignment
T2  - Scientific reports
N2  - Compressive knee joint contact force during walking is thought to be related to initiation and progression of knee osteoarthritis. However, joint loading is often evaluated with surrogate measures, like the external knee adduction moment, due to the complexity of computing joint contact forces. Statistical models have shown promising correlations between medial knee joint contact forces and knee adduction moments in particularly in individuals with knee osteoarthritis or after total knee replacements (R2 = 0.44–0.60). The purpose of this study was to evaluate how accurately model-based predictions of peak medial and lateral knee joint contact forces during walking could be estimated by linear mixed-effects models including joint moments for children and adolescents with and without valgus malalignment. Peak knee joint moments were strongly correlated (R2 > 0.85, p < 0.001) with both peak medial and lateral knee joint contact forces. The knee flexion and adduction moments were significant covariates in the models, strengthening the understanding of the statistical relationship between both moments and medial and lateral knee joint contact forces. In the future, these models could be used to evaluate peak knee joint contact forces from musculoskeletal simulations using peak joint moments from motion capture software, obviating the need for time-consuming musculoskeletal simulations.
Y1  - 2023
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/82636
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-826362
SN  - 2045-2322
N1  - Gefördert durch den Open-Access-Publikationsfonds der Goethe-Universität
VL  - 13
IS  - Article number: 2870
PB  - Macmillan Publishers Limited, part of Springer Nature
CY  - London
ER  -