TY - JOUR A1 - Archavlis, Eleftherios A1 - Ulrich, Peter A1 - Carvi y Nievas, Mario N. T1 - New developments in drug therapy and research of cerebral vasospasm T2 - Open Journal of Modern Neurosurgery N2 - In this manuscript a comprehensive coverage of recent developments in the drug therapy of vasospasm while providing the background information that neuroscientists need to understand its rationale. The range of new agents available for treatment of cerebral vasospasm is expanding rapidly along with rapid advances in pharmacology and physiology that are uncovering the mechanisms of this disease. Although there are many publications for treatment of cerebral vasospasm, most are focusing on different aspects of vasospasm treatment and many have limited value due to insufficient quality. Moreover, the complexity of this, in many cases deleterious condition, is enormous and the information needed to understand drug effects is accordingly often not readily available in a single source. A number of pharmacological and medical therapies are currently in use or being investigated in an attempt to reverse cerebral vasospasm, but only a few have proven to be useful. Current research efforts promise the eventual production of new medical therapies. At last, recommendations for the use of different treatment stages based on currently available clinical data are provided. KW - Cerebral Vasospasm KW - Drug Therapy KW - Subarachnoid Hemorrhage KW - Delayed Cerebral Ischemia KW - New Developments KW - Treatment Y1 - 2013 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/33573 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-335739 SN - 2163-0585 N1 - Copyright © 2013 Eleftherios Archavlis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. VL - 3 SP - 72 EP - 93 PB - Scientific Research Publishing CY - Irvine, CA ER -