TY  - JOUR
A1  - Neef, Vanessa
A1  - Buxmann, Horst
A1  - Rabenau, Holger
A1  - Zacharowski, Kai
A1  - Raimann, Florian
T1  - Characterization of neonates born to mothers with SARS-CoV-2 infection: review and meta-analysis
T2  - Pediatrics and neonatology
N2  - Characterization of neonates born to mothers with SARS-CoV-2 infection has been partially carried out. There has been no systematic review providing a holistic neonatal presentation including possible vertical transmission. A systematic literature search was performed using PubMed, Google Scholar and Web of Science up to June, 6 2020. Studies on neonates born to mothers with SARS-CoV-2 infection were included. A binary random effect model was used for prevalence and 95% confidence interval. 32 studies involving 261 neonates were included in meta-analysis. Most neonates born to infected mothers did not show any clinical abnormalities (80.4%). Clinical features were dyspnea in 11 (42.3%) and fever in 9 newborns (19.1%). Of 261 neonates, 120 neonates were tested for infection, of whom 12 (10.0%) tested positive. Swabs from placenta, cord blood and vaginal secretion were negative. Neonates are mostly non affected by the mother's SARS-CoV-2 infection. The risk of vertical transmission is low.
KW  - COVID-19
KW  - infant
KW  - neonate
KW  - newborn
KW  - SARS-CoV-2
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/57557
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-575578
SN  - 2212-1692
SN  - 1875-9572
VL  - 2020
PB  - Elsevier
CY  - [Singapore]
ER  -