TY - JOUR A1 - Michel, Sebastian A1 - Bigdeli, Amir Khosrow A1 - Beiras Fernández, Andrés A1 - Schmitz, Christoph A1 - Wolf, Manuel A1 - Sodian, Ralf A1 - Kaczmarek, Ingo T1 - Interdisciplinary three-step strategy to treat aortic stenosis and coronary artery disease in a patient with end-stage chronic obstructive pulmonary disease T2 - Therapeutics and clinical risk management N2 - Background: Valvular aortic stenosis is a common disease in the elderly, often in multimorbid patients. It is often associated with coronary artery disease and peripheral artery disease. In this situation, the risk of conventional open-heart surgery is too high, and other treatment strategies have to be evaluated. Case report: A 79-year-old female patient with severe aortic stenosis, coronary artery disease and end-stage chronic obstructive pulmonary disease suffering from dyspnea at rest and permanently dependent on oxygen was treated in three steps. Firstly, her pulmonary infection was treated with antibiotics for 7 days. Then, the left anterior descending artery was stented (bare-metal stent). In the same session, valvuloplasty of the aortic valve was performed. She was sent to rehabilitation to improve her pulmonary condition and took clopidogrel for 4 weeks. Finally, she underwent transapical aortic valve replacement. She was released to rehabilitation on postoperative day 12. Conclusion: A combination of modern interventional and minimally invasive surgical techniques to treat aortic stenosis and coronary heart disease can be a viable option for multimorbid patients with extremely high risk in conventional open-heart surgery. KW - aortic stenosis KW - transapical aortic valve replacement KW - minimally invasive cardiac surgery Y1 - 2012 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/25356 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-253568 SN - 1178-203X SN - 1176-6336 VL - 8 SP - 181 EP - 183 PB - Dove Medical Press CY - Albany, Auckland ER -