TY  - JOUR
A1  - Samali, Afshin
A1  - Fulda, Simone
A1  - Gorman, Adrienne M.
A1  - Hori, Osamu
A1  - Srinivasula, Srinivasa M.
T1  - Cell stress and cell death
T2  - International journal of cell biology
N2  - Editorial: This special issue on Cell Stress and Cell Death is aimed at bringing together recent developments in the fields of cellular stress and cell death and, in particular, the interplay between cell stress responses and cell death. The special issue opens with a review by S. Fulda et al. which provides an overview of how cells can respond to stress in a variety of ways ranging from the activation of survival pathways to the initiation of cell death that eventually eliminates damaged cells. Whether cells mount a protective response or succumb to death depends to a large extent on the nature and duration of the stress as well as the cell type. For example, milder stresses can lead to protection through activation of the heat shock response or the unfolded protein response (UPR). This review also describes several types of cell death (e.g., apoptosis, necrosis, pyroptosis, or autophagic cell death) and the mechanism by which a cell dies often depends on various exogenous factors as well as the cell’s ability to handle the stress to which it is exposed. The implications of cellular stress responses for human physiology and disease are multifold and are discussed in this review in the context of some major world health issues such as diabetes, Parkinson’s disease, myocardial infarction, and cancer. ...
Y1  - 2012
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/24278
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-242788
SN  - 1687-8884
SN  - 1687-8876
VL  - 2010
IS  - Article ID 245803
PB  - Hindawi
CY  - New York, NY
ER  -