TY  - JOUR
A1  - Stadler, Christina
A1  - Poustka, Fritz
A1  - Sterzer, Philipp
T1  - The heterogeneity of disruptive behavior disorders – implications for neurobiological research and treatment
T2  - Frontiers in psychiatry
N2  - Disruptive behaviour disorders are reflected by a great variety of symptoms ranging from impulsive-hot tempered quarrels to purposeful and goal directed acts of cruelty. A growing body of data indicates that there are neurobiological factors that increase the risk for developing disruptive behaviour disorders. In this review, we give a broad overview of recent studies investigating physiological, neural, genetic factors, and specific neurotransmitter systems. We also discuss the impact of psychosocial risk and consider the effects of gene-environment interactions. Due to the heterogeneity of disruptive behaviour disorders, it is concluded that specific subtypes of disruptive behaviour should be considered both in terms their biological basis and in regard to specific treatment needs.
KW  - neurobiology
KW  - aggression
KW  - conduct disorder
KW  - disruptive behaviour disorder
KW  - review
KW  - research
KW  - intervention
Y1  - 2010
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/20107
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30-83819
SN  - 1664-0640
N1  - Copyright © 2010 Stadler, Poustka and Sterzer. This is an open-access article subject to an exclusive license agreement between the authors and the Frontiers Research Foundation, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are credited.
VL  - 1
IS  - Art. 21
SP  - 1
EP  - 14
PB  - Frontiers Research Foundation
CY  - Lausanne
ER  -