TY - JOUR A1 - Abras, Marcel A1 - Surev, Artiom A1 - Vasa-Nicotera, Mariuca A1 - Moscalu, Vitalie A1 - Grib, Andrei A1 - Popovici, Ion A1 - Beiu, Cătălina T1 - Transcatheter aortic valve implantation. First experience of minimally invasive treatment in the Republic of Moldova T2 - Moldovan medical journal N2 - Background: Aortic stenosis (AS) is the most prevalent primary heart valve disease and the third most prevalent cardiovascular disease in the world, having a severe and slowly progressive evolution. The implementation of Transcatheter Aortic Valve Implantation (TAVI) is necessary because the population is constantly ageing, and most elderly people have various comorbidities, which places them among patients with high surgical risk. The aim was to report immediate and 9 months follow-up results of first TAVI implantations in the Republic of Moldova. Material and methods: Three patients with severe symptomatic AS and high surgical risk underwent TAVI implantation using Portico valves. Results: The mean age was 76.7 ± 1.2 years, 2 women and 1 man. The mean Logistic EuroSCORE II was 5.68 ± 0.67%. Procedural success was achieved in all (100%) patients. After the intervention, it was shown that the GP mean decreased by an average of 20.27±1.61 mmHg, the Vmax of the jet through AoV decreased on average by 2.05±0.19 m/s, and they were maintained all over the nine months follow-up period. Quality of life, using the TASQ (Toronto Aortic Stenosis Quality of Life) questionnaire, was improved by 62.3 ± 2.2 points. Conclusions: TAVI, as a new minimally invasive method of treatment for aortic valve stenosis appears to be safe, with a low rate of early and late complications in elderly patients at high surgical risk, with good clinical outcomes at 9 months. Its implementation in the Republic of Moldova is welcome in the conditions of continuously ageing population and the prevalence of associated comorbidities. KW - aortic stenosis KW - high surgical risk KW - Transcatheter Aortic Valve Implantation KW - elderly patients Y1 - 2020 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/50012 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-500128 SN - 2537-6381 VL - 63 IS - 3 SP - 58 EP - 65 PB - Scientific Medical Association of Moldova CY - Chișinău ER -