TY  - JOUR
A1  - Heiskel, Harald
A1  - Gunzenhäuser, Ditz
A1  - Seidler, Andreas
A1  - Volk, Stephan
A1  - Pflug, Burkhard
A1  - Kauppinen, Timo
A1  - Elsner, Gine
T1  - Sleep apnea and occupational exposure to solvents
T2  - Scandinavian journal of work, environment & health
N2  - Objectives: The possible effects of exposure to neurotoxic substances such as gasoline, diesel fuel, paint, varnish, and solvents on the pathogenesis of obstructive sleep apnea were examined.
Methods: Four hundred and forty-three persons with incident obstructive sleep apnea were recruited within the framework of a case-referent study. A reference population (N=397) was included as the first reference group. In addition 106 patients whose sleep laboratory findings confirmed that they were not suffering from obstructive sleep apnea were then included as a second reference group. Data were gathered with a questionnaire which had to be filled out by the persons with obstructive sleep apnea (cases) and the referents themselves. In the assessment of occupational exposure the questionnaires were filled out by the subjects themselves, and a job-exposure matrix was also used. Data were analyzed using logistic regression to control for age, region, body mass index, cigarette smoking, and alcohol consumption.
Results: None of the exposures were statistically significantly associated with obstructive sleep apnea. There was no correlation with occupation. Only current activities in service occupations revealed an increased odds ratio, 1.6 (95% confidence interval 1.1-2.4).
Conclusions: No suggestion was found of an association between exposure to solvents and obstructive sleep apnea.
KW  - case-control study
KW  - case-referent study
KW  - job-exposure matrix
KW  - occupational exposure
KW  - sleep apnea
KW  - solvent
Y1  - 2002
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/45604
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-456044
SN  - 1795-990X
SN  - 0355-3140
N1  - This work is licensed under a Creative Commons Attribution 4.0 International License.
VL  - 28
IS  - 4
SP  - 249
EP  - 255
PB  - Finnish Inst. of Occupational Health
CY  - Helsinki
ER  -