TY  - JOUR
A1  - Burch, Ashley E.
A1  - Erath, Julia W.
A1  - Kutyifa, Valentina
A1  - Aßmus, Birgit
A1  - Bonderman, Diana
A1  - Russo, Andrea M.
T1  - Decline in physical activity in the weeks preceding sustained ventricular arrhythmia in women
T2  - Heart rhythm O2
N2  - Background: Heightened risk of cardiac arrest following physical exertion has been reported. Among patients with an implantable defibrillator, an appropriate shock for sustained ventricular arrhythmia was preceded by a retrospective self-report of engaging in mild-to-moderate physical activity. Previous studies evaluating the relationship between activity and sudden cardiac arrest lacked an objective measure of physical activity and women were often underrepresented.
Objective: To determine the relationship between physical activity, recorded by accelerometer in a wearable cardioverter-defibrillator (WCD), and sustained ventricular arrhythmia among female patients.
Methods: A dataset of female adult patients prescribed a WCD for a diagnosis of myocardial infarction or dilated cardiomyopathy was compiled from a commercial database. Curve estimation, to include linear and nonlinear interpolation, was applied to physical activity as a function of time (days before arrhythmia).
Results: Among women who received an appropriate WCD shock for sustained ventricular arrhythmia (N = 120), a quadratic relationship between time and activity was present prior to shock. Physical activity increased starting at the beginning of the 30-day period up until day -16 (16 days before the ventricular arrhythmia) when activity begins to decline.
Conclusion: For patients who received treatment for sustained ventricular arrhythmia, a decline in physical activity was found during the 2 weeks preceding the arrhythmic event. Device monitoring for a sustained decline in physical activity may be useful to identify patients at near-term risk of a cardiac arrest.
KW  - Defibrillation
KW  - Physical activity
KW  - Ventricular arrhythmia
KW  - Wearable cardioverter-defibrillator
KW  - Women
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/77814
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-778143
SN  - 2666-5018
VL  - 1
IS  - 4
SP  - 283
EP  - 287
PB  - Elsevier
CY  - Amsterdam
ER  -