TY  - JOUR
A1  - Hirche, Tim Oliver
A1  - Knoop, Christiane
A1  - Hebestreit, Helge Uwe
A1  - Shimmin, Dee
A1  - Solé, Amparo
A1  - Elborn, Joseph Stuart
A1  - Ellemunter, Helmut
A1  - Aurora, Paul
A1  - Hogardt, Michael
A1  - Wagner, Thomas O. F.
T1  - Practical guidelines: lung transplantation in patients with cystic fibrosis
T2  - Pulmonary medicine
N2  - There are no European recommendations on issues specifically related to lung transplantation (LTX) in cystic fibrosis (CF). The main goal of this paper is to provide CF care team members with clinically relevant CF-specific information on all aspects of LTX, highlighting areas of consensus and controversy throughout Europe. Bilateral lung transplantation has been shown to be an important therapeutic option for end-stage CF pulmonary disease. Transplant function and patient survival after transplantation are better than in most other indications for this procedure. Attention though has to be paid to pretransplant morbidity, time for referral, evaluation, indication, and contraindication in children and in adults. This review makes extensive use of specific evidence in the field of lung transplantation in CF patients and addresses all issues of practical importance. The requirements of pre-, peri-, and postoperative management are discussed in detail including bridging to transplant and postoperative complications, immune suppression, chronic allograft dysfunction, infection, and malignancies being the most important. Among the contributors to this guiding information are 19 members of the ECORN-CF project and other experts. The document is endorsed by the European Cystic Fibrosis Society and sponsored by the Christiane Herzog Foundation.
Y1  - 2014
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/33468
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-334683
SN  - 2090-1844
SN  - 2090-1836
N1  - Copyright © 2014 T. O. Hirche et al. This is an open access article distributed under the   Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/ , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
VL  - 2014
IS  - Article ID 621342
SP  - 1
EP  - 22
PB  - Hindawi
CY  - New York, NY [u.a.]
ER  -