TY  - CONF
A1  - Younsi, Alexander
A1  - Unterberg, Andreas
A1  - Marzi, Ingo
A1  - Woschek, Mathias
A1  - Lemcke, Johannes
A1  - Maegele, Marc
A1  - Bendella, Habib
A1  - Mauer, Uwe Max
A1  - Scheer, Magnus
A1  - Uhl, Eberhard
A1  - Friedrich, Michaela
A1  - Meixensberger, Jürgen
A1  - Lindner, Dirk
A1  - Westermaier, Thomas L.
A1  - Stetter, Christian E.
A1  - Clusmann, Hans
A1  - Hamou, Hussam Aldin
A1  - Schmieder, Kirsten
A1  - Gierthmühlen, Mortimer
A1  - Steudel, Wolf-Ingo
T1  - The German National TBI-Registry: conception, implementation and first results
T2  - Brain and Spine
N2  - Objective: Nationwide data on the epidemiology, treatment characteristics, and long-term outcome of severe traumatic brain injury (TBI) in Germany is not yet existing. Neurosurgeons from the German Neurosurgery Society (DGNC) and traumatologists from the German Trauma Society (DGU), therefore, joined forces in 2016 to conceptualize a TBI module for the well-established Trauma Register of the DGU (TR-DGU). Here, we report how this “German National TBI registry (GNTR)” has been developed, implemented, and tested in a recently completed pilot period.
Methods: The conception and implementation process of the GNTR from August 2016 to February 2019 is described, and results of its 23-months long pilot period from February 2019 to December 2020 are presented. For the pilot period, TBI patients were prospectively enrolled at nine neurosurgical and traumatological hospitals across Germany. Inclusion criteria were treatment on the ICU ≥ 24h, or an ISS score ≥ 16. A variety of clinical, imaging, and laboratory parameters were collected, and the GOSE score was used to assess the outcome at discharge and 6- and 12 months follow-up.
Results: Details on the structure and dataset of the GNTR as well as milestones and pitfalls during its conception and implementation, are outlined. During the pilot period, a total of 264 TBI patients were enrolled. Their demographic characteristics, clinical, imaging, and radiological findings, and their early mortality and functional outcome are described. Furthermore, factors associated with an unfavorable outcome (GOSE 1-4) are assessed using uni- and multivariate regression analyses. Finally, problems and future directions of the GNTR are discussed.
Conclusion: The pilot period of the GNTR offers a first glance at the current epidemiology and treatment characteristics of TBI patients in Germany. More importantly, they show how a national TBI registry yielding high-quality prospective data can be developed, implemented, and tested within four years
Y1  - 2021
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/78135
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-781356
SN  - 2772-5294
VL  - 1
IS  - supplement 2, 100633
PB  - Elsevier
CY  - Amsterdam
ER  -