TY - JOUR A1 - Mayer, Jutta A1 - Brandt, Geva A. A1 - Medda, Juliane A1 - Basten, Ulrike A1 - Grimm, Oliver A1 - Reif, Andreas A1 - Freitag, Christine M. T1 - Depressive symptoms in youth with ADHD: the role of impairments in cognitive emotion regulation T2 - European archives of psychiatry and clinical neuroscience N2 - Youth with attention-deficit/hyperactivity disorder (ADHD) are at increased risk to develop co-morbid depression. Identifying factors that contribute to depression risk may allow early intervention and prevention. Poor emotion regulation, which is common in adolescents, is a candidate risk factor. Impaired cognitive emotion regulation is a fundamental characteristic of depression and depression risk in the general population. However, little is known about cognitive emotion regulation in youth with ADHD and its link to depression and depression risk. Using explicit and implicit measures, this study assessed cognitive emotion regulation in youth with ADHD (Nā€‰=ā€‰40) compared to demographically matched healthy controls (Nā€‰=ā€‰40) and determined the association with depressive symptomatology. As explicit measure, we assessed the use of cognitive emotion regulation strategies via self-report. As implicit measure, performance in an ambiguous cue-conditioning task was assessed as indicator of affective bias in the processing of information. Compared to controls, patients reported more frequent use of maladaptive (i.e., self-blame, catastrophizing, and rumination) and less frequent use of adaptive (i.e., positive reappraisal) emotion regulation strategies. This pattern was associated with the severity of current depressive symptoms in patients. In the implicit measure of cognitive bias, there was no significant difference in response of patients and controls and no association with depression. Our findings point to depression-related alterations in the use of cognitive emotion regulation strategies in youth with ADHD. The study suggests those alterations as a candidate risk factor for ADHD-depression comorbidity that may be used for risk assessment and prevention strategies. KW - Attention-deficit/hyperactivity disorder KW - ADHD KW - Depression KW - Major depressive disorder KW - Comorbidity KW - Emotion regulation KW - Implicit KW - Explicit KW - Cognitive Y1 - 2022 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/69565 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-695655 SN - 1433-8491 N1 - Open Access funding enabled and organized by Projekt DEAL. The research has received funding from the EU Framework Programme for Research and Innovation, Horizon 2020 under Grant Agreement No. 667302 (CoCA). VL - 272 IS - 5 SP - 793 EP - 806 PB - Steinkopff , Springer CY - Darmstadt , Berlin ; Heidelberg ER -