TY  - JOUR
A1  - Münchhoff, Maximilian
A1  - Mairhofer, Helga
A1  - Nitschko, Hans
A1  - Grzimek-Koschewa, Natascha
A1  - Hoffmann, Dieter
A1  - Berger, Annemarie
A1  - Rabenau, Holger
A1  - Widera, Marek
A1  - Ackermann, Nikolaus
A1  - Konrad, Regina
A1  - Zange, Sabine
A1  - Graf, Alexander
A1  - Krebs, Stefan
A1  - Blum, Helmut
A1  - Sing, Andreas
A1  - Liebl, Bernhard
A1  - Wölfel, Roman
A1  - Ciesek, Sandra
A1  - Drosten, Christian
A1  - Protzer, Ulrike
A1  - Böhm, Stephan
A1  - Keppler, Oliver Till
T1  - Multicentre comparison of quantitative PCR-based assays to detect SARS-CoV-2, Germany, March 2020
T2  - Eurosurveillance
N2  - Containment strategies and clinical management of coronavirus disease (COVID-19) patients during the current pandemic depend on reliable diagnostic PCR assays for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we compare 11 different RT-PCR test systems used in seven diagnostic laboratories in Germany in March 2020. While most assays performed well, we identified detection problems in a commonly used assay that may have resulted in false-negative test results during the first weeks of the pandemic.
KW  - COVID-19
KW  - PCR
KW  - SARS-CoV-2
KW  - diagnostic test
Y1  - 2020
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/54734
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-547349
SN  - 1560-7917
N1  - This work is licensed under a Creative Commons Attribution 4.0 International License.
VL  - 25
IS  - 24, Art. 2001057
SP  - 1
EP  - 5
PB  - European Centre for Disease Prevention and Control
CY  - Stockholm
ER  -