TY - JOUR A1 - Grundmann, Florian A1 - Dill, Veronika A1 - Dowling, Andrea A1 - Thanwisai, Aunchalee A1 - Bode, Edna A1 - Chantratita, Narisara A1 - ffrench-Constant, Richard A1 - Bode, Helge Björn T1 - Identification and isolation of insecticidal oxazoles from Pseudomonas spp. T2 - Beilstein journal of organic chemistry N2 - Two new and five known oxazoles were identified from two different Pseudomonas strains in addition to the known pyrones pseudopyronine A and B. Labeling experiments confirmed their structures and gave initial evidence for a novel biosynthesis pathway of these natural oxazoles. In order to confirm their structure, they were synthesized, which also allowed tests of their bioactivity. Additionally, the bioactivities of the synthesis intermediates were also investigated revealing interesting biological activities for several compounds despite their overall simple structures. KW - insecticidal activity KW - labradorin KW - oxazole KW - Pseudomonas KW - secondary metabolite Y1 - 2012 UR - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/28879 UR - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-288799 SN - 1860-5397 N1 - Copyright © 2012, Grundmann et al; licensee Beilstein-Institut. This is an Open Access article under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (http://www.beilstein-journals.org/bjoc) VL - 8 SP - 749 EP - 752 PB - Frankfurt, Main CY - Beilstein-Institut zur Förderung der Chemischen Wissenschaften ER -