TY  - INPR
A1  - Canet Pons, Júlia
A1  - Schubert, Ralf
A1  - Dücker, Ruth Pia
A1  - Schrewe, Roland
A1  - Wölke, Sandra
A1  - Schnölzer, Martina
A1  - Auburger, Georg
A1  - Zielen, Stefan
A1  - Warnken, Uwe
T1  - Ataxia Telangiectasia triggers deficits in Reelin pathway
T2  - bioRxiv
N2  - Autosomal recessive Ataxia Telangiectasia (A-T) is characterized by radiosensitivity, immunodeficiency and cerebellar neurodegeneration. A-T is caused by inactivating mutations in the Ataxia-Telangiectasia-Mutated (ATM) gene, a serine-threonine protein kinase involved in DNA-damage response and excitatory neurotransmission. The selective vulnerability of cerebellar Purkinje neurons (PN) to A-T is not well understood.
Y1  - 2018
UR  - http://publikationen.ub.uni-frankfurt.de/frontdoor/index/index/docId/72483
UR  - https://nbn-resolving.org/urn:nbn:de:hebis:30:3-724830
IS  - 336842
ER  -